It has long been presumed that alpha-lipoic acid can aid in the control of glucose by increasing the speed in which the blood sugar is metabolized. This could potentially aid in the treatment of diabetes, a disease characterized by abnormally high blood glucose levels.
A 2018 systematic review and meta-analysis of 20 randomized controlled trials of people with metabolic disorders (some had type 2 diabetes, others had other metabolic disorders) found that lipoic acid supplementation lowered fasting blood glucose, insulin concentration, insulin resistance, and blood hemoglobin A1C levels.
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